Impact on survival of a second primary melanoma

October 24, 2016

Abstract

The impact on survival of a second primary melanoma (SPM) is unclear. We used our melanoma center’s database to examine clinicopathologic risk factors and outcomes of stage 0 to IV cutaneous melanoma in patients with one versus two primaries.

Among 12,325 patients with primary melanoma, 969 (7.86%) developed SPM. SPMs were significantly thinner than autologous primary melanomas (P = 0.01), and 451 SPM patients had better overall and melanoma-specific survival than 451 prognostically matched non-SPM patients (P < 0.0001 and 0.0001, respectively) at a median follow-up of 142.37 months.

Patients with cutaneous melanoma are at high risk for development of SPM, but the development of SPM does not seem to impair survival.

Source:

Jones, M.S., et al. Second Primary Melanoma: Risk Factors, Histopathologic Features, Survival, and Implications for Follow-Up. The American Surgeon, Volume 82, Number 10, October 2016, pp. 1009-1013(5)  http://www.ingentaconnect.com/...