Despite novel approaches of combination treatments, resistance to combination therapies is rapid and common, according to authors of this recent review. They conclude that new treatment strategies may require triple or more complex drug combinations.
This ASCO Reading Room article summarises current evidence regarding the use of checkpoint inhibitors in melanoma with a specific focus on quality of life and use of healthcare resources.
Circulating tumor DNA (ctDNA) has a powerful role in monitoring metastatic melanoma, according to authors of this study.
Findings of this study suggest that, rather than continuing to educate sunbed users about the risks, campaigns and interventions should challenge the commonly drawn upon arguments about the health benefits.
Both visual and written communication should be considered when designing an effective skin self-examination programme, according to this recent study.
Thin melanomas are a substantial public health burden, despite excellent prognosis, according to an analysis of SEER data in the United States. The authors conclude that “efforts should be made to diagnose melanoma at the in situ stage”.
Findings of this study suggest that a person’s risk factor status could be used to tailor surveillance programs and education about skin self-examination.
Patients treated with stereotactic radiotherapy (SRT) and immunotherapy have a higher incidence/risk of intracranial complications, but a longer overall survival, according to authors of this study.
Results of this study indicate that pregnancy or post partum [pregnancy-associated melanoma (PAM)] is associated with a worse prognosis than melanoma not related to pregnancy, both in terms of overall survival and disease-free survival, according to its authors.
Regional radiation therapy was associated with a reduced risk of regional recurrence among patients with ECE (extracapsular extension) and clinically detected nodal disease, according to the results of a single institution study. The authors conclude that “in the era of increasingly effective systemic therapies, the value of improved regional control potentially takes on greater significance”.