Data from a recent study suggest that de novo melanomas are more aggressive than nevus-associated melanomas. Also the overall survival of patients with nevus-associated melanomas is also better than that of patients with de novo melanomas.
Epidemiologic and clinical difference for in situ and invasive melanomas support further examination into the variations in etiologic pathways, according to authors of a recent study.
Opdivo maintained or improved baseline health-related quality of life for patients with advanced melanoma, according to quality-of-life analyses of the CheckMate 066 phase 3 study.
Analysing biopsies from melanoma patients before the start of treatment cannot reliably predict. Measuring immune response in tumor biopsies during early treatment could help predict which patients will respond to treatment, according to a study published in the journal Cancer Discovery.
"New approaches are needed to minimise reactance responses in adolescents while fostering favourable attitudes to sun protection", according to authors of an Australian study. Their journal article provides both study implications and opportunities for interventions to promote better sun-protection practices among adolescents.
Study results support further study of topical imiquimod combined with vaccines or other immune therapies for the treatment of melanoma
This recent open access “NCCN Guidelines Insights” publication summarises the data and rationale supporting extensive changes to the recommendations for systemic therapy in patients with metastatic or unresectable melanoma.
Individuals with melanoma who worry most about the future may do so because of the cumulative effects of stress (both disease and non-cancer related) and a perceived lack of support from healthcare teams and within their lives generally, according to the results of this population-based study.
Clinical management of higher risk patients was more likely to conform to clinical practice guidelines for diagnosis and skin surveillance than to melanoma patients at lower risk, according to the result of a recent Australian study.
Morphologic characteristics (ie, structures and patterns), not colour, provide the primary diagnostic clue in dermoscopy, according to authors of this study. They also conclude that the use of gray-scale images may improve the teaching of dermoscopy to novices by emphasising the evaluation of morphology.