The objective of this recent study was to further develop the technique of using tape strip derived ribonucleic acid (RNA) to distinguish cutaneous malignant melanoma (CMM) from nevi and validate if RNA profiles can rule out CMM in clinically suspicious lesions with 100% sensitivity. The study concludes that the technique can reduce removal of benign lesions by one-third without overlooking any CMMs.
This article provides a review of dermoscopic melanoma criteria according to specific body sites, including frequently observed melanoma of the head/neck, trunk and limbs and special site melanomas, located on the nail, mucosal and acral region.
According to this recent study, dermatologists may improve their performance when they cooperate with the market-approved Convolutional Neural Network and that a broader application of this human with machine approach could be beneficial for dermatologists and patients.
According to this recent study, New Zealand is a high-risk population for nodal melanoma metastases. The conclusions of the second Multicenter Selective Lymphadenectomy Trial (MSLT-II) may not be able to be applied to melanoma patients in the 7 regions studied in New Zealand.
According to this recent study there is a clear association between earlier stage at skin cancer detection and decreased mortality risk. Results suggest no melanoma mortality benefit associated with skin cancer screening in adolescents or adults in regions with implemented routine screening compared to regions without routine screening. Results suggest no association between routine clinician skin examination and earlier stage at melanoma detection. There appears to be little direct evidence on harms of screening.
According to this recent study, melanoma brain metastasis patients treated with either ipilimumab–nivolumab or nivolumab did not report a significant deterioration in health-related quality of life within 18 weeks of treatment initiation, providing support for the use of these immunotherapies as first-line treatment for melanoma brain metastases.
This recent study explores the impact of liquid–liquid phase separation (LLPS)-related genes on melanoma prognosis. It concludes that the gene signature can independently predict the survival of melanoma patients and provides a basis for the exploration of the relationship between LLPS and melanoma.
According to this recent research, supportive care interventions have positive impacts on melanoma patient well-being outcomes, while being acceptable and feasible to conduct. Authors state that more research was needed regarding supportive care interventions for melanoma caregivers.
This review provides an overview of the screening, diagnosis and management of melanoma in Australia.
Review on genetics related to melanoma tumorigenesis, metastasis, and prognosis, and on genetics affecting the melanoma tumor microenvironment and its relation to tumor progression and treatment.