Overview of skin cancer: Pathogenesis, conventional treatment strategies, and nano-carrier based approaches for delivery of nutraceuticals through skin
January 14, 2021
Abstract
Skin cancer has one of the highest incidences of any type of cancer with an increasing incidence rate worldwide. It is
life-threatening and has led to immense economic and human loss all over the world. The conventional treatment
strategies have profound adverse effects, which necessitated the development of novel methods. Nutraceuticals are
naturally occurring compounds, and they were reported to exhibit great efficacy in cancer treatment and prevention.
Accordingly, topical delivery of nutraceuticals can be considered the most optimum approach for the efficient and
safe treatment of skin cancer. However, the utmost challenge to topical drug delivery is the impermeable nature of
the skin which hinders drug penetration/permeation. Hence, the use of vesicular delivery systems for nutraceuticals
has been a chief research area for years. In this review, we overview skin cancer with its pathogenesis, conventional
treatment strategies, and the nano-carrier based approaches for the delivery of nutraceuticals through the skin.
Source:
Bayoumi M, Arafa M, Nasr M, Sammour O, 2020. Skin cancer therapy: From conventional to nutraceutical based nanovesicular carriers. Arch Pharm Sci ASU 4(2): 253-26