The PROVE-AI study looks to validate the accuracy of an open-source, non-commercial AI algorithm for melanoma diagnosis and assess its potential impact on dermatologist decision-making.
This recent study sought to determine the mechanisms underlying radioresistance in melanoma cell lines in order to improve clinical efficacy of radiation therapy.
This recent study looked at long-term outcomes for stage III/IV melanoma patients treated with neoadjuvant and adjuvant PD-1 inhibition. Five-year results demonstrated long-term efficacy of single-agent neoadjuvant/adjuvant PD-1 blockade in patients with a complete pathological response and the importance of long-term follow-up for these patients.
This study examined the association between SMARCD1 expression and numerous factors in order to demonstrate that SMARCD1 is a promising diagnostic, prognostic, and therapeutic biomarker for skin cutaneous melanoma.
This recent study demonstrated that lactate dehydrogenase has independent prognostic value for patients with melanoma brain metastases and might be used to improve prognostic stratification.
This study sought to construct a usable matrix of ultra violet radiation exposure across 250 occupations based on data obtained from 1000 individuals who wore electronic data logger dosimeters during their working time over a 7-month period. Information from the detailed datasets may be extrapolated for use in other countries, including NZ to aid in identifying high-risk occupational activity.
This study reports recurrence-free survival and overall survival results for participants with stage III melanoma from the OpACIN and OpACIN-neo trials. Data confirms the high survival rates after neoadjuvant combination checkpoint inhibition in macroscopic stage III melanoma, especially for patients with a pathologic response. Pathologic response is the strongest surrogate marker for long-term outcome.
This study uses UK mortality rates between 2018 and 2022 to create a life expectancy predictive scoring system for elderly UK populations. This work is intended to support decision-making when considering surgical intervention for BCC in elderly patients.
This recent review compared sun protection legislation and guidelines in the Group of Seven, Australia and New Zealand. It recommended that countries should legislate sun protective behaviors and infrastructure in schools, childcare, sports and recreation settings, enact stringent sunscreen and UVR-textile manufacturing standards, implement favorable taxation policies for sun protective equipment and over-the-counter products and ban sunbeds.
This recent study aimed to quantify adult preferences for adjuvant immunotherapy for resected melanoma. The study concludes that almost three-quarters of respondents chose adjuvant immunotherapy over no adjuvant immunotherapy, preferring treatment that improved efficacy and safety. Findings may inform decisions about access to adjuvant immunotherapy following surgery for melanoma.