9 June 2021This recent study evaluates the role of local therapy for solitary progression in melanoma. It concludes that almost half of patients with melanoma treated for solitary progression after initial response to immune checkpoint inhibition had no subsequent progression. The study suggests that local therapy can benefit patients and is associated with favourable long-term outcomes.
9 June 2021This review provides an overview of the various options for treating melanoma patients with nodal metastases and discusses the data that supported the development of these treatment options.
9 June 2021According to this recent review, the increasing knowledge of hypoxia-regulated pathways in melanoma progression and the promising results obtained from novel antiangiogenic therapies could offer new perspectives in clinical practice in order to improve survival outcomes of melanoma patients.
27 May 2021This recent study aimed to evaluate the progression-free survival (PFS) of patients with metastatic melanoma after anti-PD-1 interruption for objective response (OR) or limiting toxicity during clinical trials. The cohort of the study shows a global recurrence rate of 18.5% and confirms a long-lasting response after anti-PD-1 cessation regardless of the cause of discontinuation.
17 May 2021This trial will assess the effectiveness of a developed patient decision aid to enhance patient knowledge of treatment options for metastatic melanoma, shared decision-making, and patient decision satisfaction.
17 May 2021According to this recent study, regression was a favorable prognostic factor for patients with stage 1 and 2 melanomas, especially in those with thin and intermediate thickness tumors and those with superficial spreading melanoma (SSM) subtype.
17 May 2021The aim of this recent study was to understand the use of diagnostic aids amongst Australian general practitioners (GPs) and dermatologists. The study cioncludes that dermoscopy, sequential digital dermoscopy imaging (SDDI) and total body photography (TBP) were commonly used by responding Australian skin cancer GPs and dermatologists in this survey. Automated diagnostic tools were not reported to be used routinely. Several barriers were identified for use of TBP.
17 May 2021This recent study aimed to assess clinical findings in Caucasian acral lentiginous melanoma (ALM) patients and compare the data with a matched cohort of superficial spreading melanoma (SSM) patients. The study concludes that patients with ALM have no worse outcome than non-ALM patients when correcting for significant prognostic factors.
17 May 2021The purpose of this recent study was to critically review literature supporting Mohs micrographic surgery and staged excision in treating primary cutaneous melanoma. The study concludes that longer follow-up times, clear tumor classifications, and prospective, randomized study designs are necessary to improve the quality of future research.
16 May 2021This recent study reviews the available literature to classify and describe predictive biomarkers for checkpoint inhibition in melanoma with the aim of helping clinicians in the decision-making process. The authors also performed a meta-analysis on the predictive value of PDL-1.
