This recent study identifies several challenges in continuing to reduce indoor tanning in the United States. Youth access legislation may be effective for reducing tanning among the broader population of tanners; however, there remains a need for focus on highly frequent tanners, as well as men.
Metastatic uveal melanoma is less well understood than its primary counterpart, has a distinct biology compared to skin melanoma, and lacks effective treatments. This study represents the largest whole-genome analysis of uveal melanoma to date, and presents an updated view of the metastatic disease.
This recent study investigated how C reactive protein (CRP) impacted the function of T cells and dendritic cells (DCs) from patients with melanoma. Findings suggest that high levels of CRP induce an immunosuppressive milieu in melanoma and support the blockade of CRP as a therapeutic strategy to enhance immune checkpoint therapies in cancer.
According to this recent study, oncolytic adenovirus ORCA-010 is a valuable immunotherapeutic agent for melanoma.
The Great Debate session at the 2019 Melanoma Bridge congress (December 5-7, Naples, Italy) featured counterpoint views from experts on five topical issues in melanoma.
According to this recent study, the contribution of environmental damage to melanoma likely extends beyond genetic damage to affect cell division. Sex and age determine the final mutational composition of melanoma.
Patients diagnosed with keratinocyte cancer (KC) experience heightened risk for melanoma, yet patients who go on to develop this malignancy have not been well-characterized. According to this recent study, in addition to pigmentary traits, ultraviolet radiation (UVR)-related factors, and clinical features of KC such as anatomic site may be useful in identifying patients at increased risk for melanoma after KC.
This recent study investigated the performance of the automated risk assessment of an app by comparing its assessment to that of a dermatologist in lesions selected by the participants.It concludes that the rating of the automated risk assessment was poor, and that further investigations about the diagnostic accuracy in real‐life situations are needed to provide consumers with reliable information about this healthcare application.
Melanoma‐associated retinopathy (MAR) is a rare paraneoplastic autoimmune manifestation of cutaneous malignant melanoma. Early recognition of MAR can precede the diagnosis of primary or metastatic malignant melanoma. The focus of this review article is to raise awareness of MAR and present the latest evidence relating to the investigation and management of this condition.
The purpose of this recent study was to identify the clinicopathological factors associated with fatal thin melanomas. It concludes that scalp location is a strong prognostic factor of death from thin melanoma, and that melanomas with a thickness of 0·80–1·00 mm are the more hazardous thin lesions.