According to this recent study, models developed by Melanoma Institute Australia (MIA) offer accurate and personalized estimates of both recurrence-free survival and overall survival in patients with stage II melanoma, even in the absence of pathological staging with sentinel node biopsy.
According to this recent study, merging the knowledge of dermatologists with Convolutional Neural Networks (CNNs) showed high performances for melanoma detection, encouraging collaboration between computer science and medical fields.
This objective of this article is to offer insights and recommendations for the present and future deployment of AI-assisted smartphone apps and web-based services for skin diseases with emphasis on skin cancer detection. The article concludes that the utilisation of AI-assisted smartphone apps and web-based services in diagnosing and treating skin diseases has the potential to greatly benefit patients in their dermatology journeys. By prioritising innovation, fostering collaboration and implementing effective regulations, we can ensure the successful integration of these apps into clinical practice.
This recent study supports the possibility that an association exists between statin use and reduced disease recurrence in resected cutaneous melanoma.
According to this recent study, photoacoustic imaging is a promising technique for assessing the status of the skin without a surgical procedure. The capability of the modality to image microvasculature, visualize tumor boundaries, detect metastases in lymph nodes, perform fast and label-free histology, and identify circulating tumor cells could aid in the early diagnosis and classification of cutaneous melanoma, including determination of metastatic status, and could be useful for monitoring treatment efficacy noninvasively.
Spatial imaging technologies are being increasingly used to study the melanoma tumor microenvironment. The goal of such studies is to understand the complex interplay between the stroma, melanoma cells, and immune cell-types as well as their association with treatment response. According to this recent study, spatial imaging technologies are just beginning to transform our understanding of melanoma biology, providing new avenues for biomarker discovery and therapeutic development, and holding great promise for advancing personalized medicine to improve patient outcomes in melanoma and other solid malignancies.
Changes in the standard of care have led to some interest in abandoning surgical nodal staging via the sentinel lymph node biopsy procedure in melanoma patients. According to this recent article, while it is certainly possible that additional changes in melanoma therapy will make sentinel lymph node biopsy obsolete in the future, at present it remains a minimally invasive, low morbidity means of improving both staging and outcomes.
Immune checkpoint inhibitors are frequently associated with the development of immunotherapy-related adverse events (irAEs). The exact etiology, including the role of environmental factors, remains incompletely understood. According to this recent study, environmental factors that are associated with particular seasons may contribute to the development of certain irAEs and suggest the potential effect of environmental triggers. The identification of these factors may enhance preventive and therapeutic strategies to reduce the morbidity of irAEs.
Authors of this manuscript critically reviewed the most updated literature data on the landscape of predictive factors in metastatic melanoma treated with immune checkpoint inhibitors (ICIs). They focus on the principal limits and potentiality of different methods, shedding light on the more promising biomarkers.
According to this study, community pharmacies can play a positive role in skin cancer counseling. A broad range of citizens was reached and triggered to purchase sunscreen, often on the same day as the counseling. Citizens receiving additional counseling were more likely to visit a dermatologist within 180 days.