Archive:
Dec 16, 2025, 12:00 AM
Genomic copy-number variants drive apoptotic evasion underlying acquired resistance to immune checkpoint inhibitors
Patients who initially respond to immune checkpoint inhibitors (ICIs) often relapse. Here, we studied how disease-progressive (DP) clinical melanomas evolve genomically to acquire ICI resistance. Comp…
Review of keratinocyte carcinoma
Importance: Keratinocyte carcinomas are skin cancers that arise from keratinocytes and are composed of basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (cSCCs). Keratinocyte carcino…
Stage II melanoma: Is there a “simple trick” to significantly improve event-free survival?
On occasion, a therapeutic development makes a meaningful difference in patient outcomes without involvement of a new, expensive drug. An outstanding example of this in melanoma is the adoption of neo…