Dec 23, 2025, 12:00 AM
Tanning bed radiation induces melanoma by increasing mutation burden of melanocytes and by mutagenizing a broader field of melanocytes
Tanning bed users have a significantly increased risk of melanoma, but it remains unclear how indoor tanning drives melanomagenesis. To better understand the etiology of melanoma associated with tanni…
Polymer nanofiber-based electrodes for tyrosinase detection in melanoma diagnosis: scalable, cost-effective melanoma screening
The rising global incidence of melanoma and its high mortality rates due to late diagnosis demand rapid, sensitive, and non-invasive diagnostic tools. Here, we introduce a disposable electrochemical b…
Dermatoscopy may offer valuable prognostic insights into melanoma’s biological behavior before excision and help guide therapeutic decisions
Current melanoma prognostic tools have limited clinical use at the bedside, highlighting the need for more effective biomarkers. Dermatoscopy correlates with established prognostic markers obtained th…
Review: cutaneous melanoma in the context of aging
Ageing is sustained by a complex network of cellular and molecular mechanisms. The main mechanisms are cellular senescence, telomere attrition, gene expression changes, metabolic dysregulations, oxida…
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Semaphorin 5 A is a novel player of melanoma aggressiveness and progression
Introduction: Metastatic potential and rising incidence make cutaneous melanoma a major health concern worldwide. While current therapies have proven effective, they are limited by side effects arisin…
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Circulating IFNγ-associated protein signatures predict response to neoadjuvant immunotherapy in patients with stage III melanoma
Background: Immune checkpoint inhibitors (ICIs), such as anti-programmed cell death protein 1 (PD-1) and anti-cytotoxic T-lymphocyte associated protein 4 (CTLA-4), have transformed the management of s…