Mar 24, 2025, 12:00 AM
Specific pathways and marker genes in peripheral CD4+T-cells may predetermine melanoma staging and immunotherapy resistance
Background and purpose: Promoting adaptive immunity with ICIs has drastically improved melanoma prognosis, but not for all patients. Some cases relapse in the first few months, while others keep dura…
Patients with resected stage IIB/C melanoma treated with adjuvant nivolumab demonstrated stable health-related quality of life, minimal bother from side effects
Background: In the phase 3 CheckMate 76 K trial, adjuvant nivolumab significantly improved recurrence-free survival and distant metastasis-free survival versus placebo in patients with resected stage …
Significant reduction in surgical interventions for melanoma in upcoming years
Melanoma surgery has evolved from elective lymph node dissection (ELND) to sentinel lymph node biopsy (SLNB) and wide local excision (WLE) margins have come down from 5 cm to nowadays 1 – 2 cm. Recent…
Read more about 'Significant reduction in surgical interventions for melanoma in upcoming years'...