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May 19, 2025, 12:00 AM

EGFR overexpression emerges as potential predictive biomarker for responsiveness to second-line ICIs in BRAFi/MEKi-resistant melanoma

Background:  Resistance to BRAF and MEK inhibitors (BRAFi/MEKi) in metastatic melanoma frequently results in cross-resistance to immune checkpoint inhibitors (ICI), limiting effective treatment option…

Read more about ' EGFR overexpression emerges as potential predictive biomarker for responsiveness to second-line ICIs in BRAFi/MEKi-resistant melanoma'...

Posted in Research; Posted 4 months ago 2 Minute(s) to read

Toolbox for prevention of skin cancer among outdoor workers led to reduction of internal UVR exposure, consistent with self-reported increase in sunscreen use

Introduction:  Due to ultraviolet radiation (UVR) exposure at work, outdoor workers face a higher risk of keratinocyte carcinoma (KC) than indoor workers. This study evaluates the short-term effective…

Read more about 'Toolbox for prevention of skin cancer among outdoor workers led to reduction of internal UVR exposure, consistent with self-reported increase in sunscreen use'...

Posted in Research; Posted 4 months ago 2 Minute(s) to read