Archive:
Aug 18, 2025, 12:00 AM
Evaluation of nivolumab and ipilimumab for the treatment of resectable stage III melanoma: Improved outlook for patients with Stage III melanoma
Introduction: Twenty years ago, surgery was the centerpiece of treatment for cutaneous melanoma, including for resectable stage III and IV patients. The arrival of effective systemic therapies in the…
Clinicopathologic gene expression profile (CP-GEP) model can reduce number of unnecessary SLNBs performed
Context & aim: Sentinel lymph node biopsy (SLNB) is an invasive procedure that detects microscopic nodal metastasis, crucial for accurate staging and optimal management. In melanoma, most patients wh…
Outcomes of pembrolizumab in advanced melanoma by age and sex
Background: Immune checkpoint inhibitors are standard treatment for advanced melanoma. Pembrolizumab (programmed cell death-1 inhibitor) monotherapy is recommended as first-line treatment. However, r…
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