Importance:   Patients with melanoma are at risk of developing subsequent cutaneous malignant neoplasms, and the effect of prior immunotherapy is unknown. Objective:   To analyze new skin cancers in …

Read more about 'Findings of randomized clinical trial support use of adjuvant pembrolizumab in high-risk stage II melanoma'...

Posted in Research; Posted 4 days ago 2 Minute(s) to read

Ultraviolet (UV)-induced DNA mutations generate genetic drivers of cutaneous melanoma and numerous neoantigens that can trigger anti-tumor immunity. Melanoma cells must therefore rapidly evade immune …

Read more about 'Transcription factor HOXD13 drives melanoma growth and immune evasion'...

Posted in Research; Posted 4 days ago 1 Minute(s) to read

Background: Skin cancers, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), cutaneous melanoma (CM) and acral melanoma (AM), exhibit profound heterogeneity in clinical behaviour and…

Read more about 'Integrative single-cell analysis uncovers distinct tumour microenvironment ecotypes and immune evasion across skin cancers'...

Posted in Research; Posted 4 days ago 2 Minute(s) to read

Issue Addressed: With high skin cancer rates, Australia faces challenges in encouraging young people to think differently about their sun protection behaviours, particularly in an evolving media envir…

Read more about 'Formative research to inform an Australian innovative mass-reach national skin cancer prevention campaign'...

Posted in Research; Posted 4 days ago 2 Minute(s) to read