Archive:

Mar 15, 2026, 12:00 AM

Melanoma brain metastasis: new molecular insights and therapeutic directions

Melanoma, a highly aggressive and metastatic cancer, poses significant challenges due to its propensity to spread to distant organs, with brain metastasis representing a particularly devastating compl…

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Ancestry and somatic profile indicate acral melanoma origin and prognosis

Acral melanoma, which is not ultraviolet-associated, is the type of melanoma reported most commonly in several non-European-descent populations1,2,3, including in Mexican people4. Latin American sampl…

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Real-world evidence on adverse event management and time on therapy with adjuvant dabrafenib plus trametinib in patients with BRAF V600-mutant melanoma

Background/Objectives: Malignant melanoma is a highly aggressive cancer associated with significant mortality, underscoring the need for continued research efforts. COMBI-EU (NCT03944356) is a prospe…

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