Aug 25, 2025, 12:00 AM
The epiMelanoma test enables plasma-based detection of melanoma and prediction of immunotherapy response
Background: Melanoma is one of the most serious skin cancers worldwide, often progressing without obvious symptoms. Early detection is crucial to enable timely intervention, reducing morbidity and mor…
Systematic review of molecular basis of BRAF inhibitor resistance in melanoma
Background: Melanoma, the deadliest human skin cancer, frequently harbors activating BRAF mutations, with V600E being the most prevalent. These alterations drive constitutive activation of the MAPK p…
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COVID‐19 pandemic contributed to delayed melanoma diagnoses and shift towards more advanced disease at presentation
Background: The COVID‐19 pandemic has significantly disrupted global healthcare systems. Melanoma, a highly aggressive skin cancer whose prognosis is closely tied to early detection, has been particu…
Comparison between cutaneous, mucosal, acral, nail, and ocular melanoma malignancy
A melanoma is a malignant neoplasm that originates from melanocytes. Melanocytes are found in various body sites—they are most commonly found in the skin (including acral sites and nail units), ocular…
A diagnosis of dysplastic naevus has no clinical relevance and unnecessarily confounds therapeutic decision-making
The term ‘dysplastic naevus’ first introduced in 1980, has since engendered considerable debate regarding its ontological legitimacy, the appropriateness of its nomenclature, and its potential prognos…