Category: Research
ASPREE trial: Aspirin did not significantly affect keratinocyte carcinoma (KC) incidence in older Australians, but decreased the rate of multiple KC
Keratinocyte carcinomas (KC) are the most frequent cancers diagnosed in Australia and impart the largest economic cost of all cancers. Predisposed individuals tend to develop multiple KC over their li…
Clinical, pathological and molecular characteristics of patients with disease recurrence despite pathologic response to neoadjuvant ipilimumab plus nivolumab in stage III melanoma
Background: Pathologic response has been shown to be strongly associated with long-term event-free survival after neoadjuvant ipilimumab plus nivolumab in stage III melanoma. Only a small proportion o…
Impact of lidocaine concentration on analgesic efficacy and adverse events in dermatologic infiltrative anesthesia
Introduction: Infiltrative anesthesia with lidocaine plays a vital role in pain management during dermatologic procedures, ensuring patient comfort throughout the process. Objective: We aimed to in…
Uveal melanoma: a clear need exists to better define local practices and outcomes to inform future surveillance guidelines
Background: Uveal melanoma (UM) is the most common primary intraocular tumour. Despite effective local therapies, UM has a high risk of metastatic recurrence, most frequently to the liver. A signific…
Reduction in survival among melanoma survivors with second primary cutaneous and non-cutaneous melanoma
Background: Melanoma survivors have a high risk of developing second primary neoplasms, both cutaneous melanoma (SPCM) and non-cutaneous melanoma (SPNCM), but little is known about the survival impac…
Utility of rhenium-SCT as a single-session, non-invasive treatment for non-melanoma skin cancer: 1-year results from EPIC-skin study
Purpose: Rhenium-skin cancer therapy (SCT) is an innovative, noninvasive radionuclide treatment for nonmelanoma skin cancer (NMSC), which is administered in a single outpatient treatment session. A gl…
Individualised mRNA vaccines for melanoma: current status and outlook
Immunotherapy, consisting mainly of immune checkpoint inhibitors, has been successfully employed in the treatment of early and advanced-stage melanoma for more than ten years. Personalized mRNA vaccin…
Read more about 'Individualised mRNA vaccines for melanoma: current status and outlook'...
Lessons from neoadjuvant immunotherapy in melanoma: understanding antitumour immunity and tumour escape
Immunotherapy has become a fourth pillar of cancer therapy, alongside surgery, radiotherapy and chemotherapy. Cancer immunotherapy seems to be most effective in the context of low but not negligible t…
Effective sunscreen application: changes to labelling regulation required to ensure consumers receive clear, accurate and consistent information
Objective: To explore consumer understanding of regulated claims and expert recommendations for effective sunscreen application. Methods: We used a Pragmatic Qualitative Research Design to explore su…
Need for a coordinated global response to climate change and its impact on skin cancer
Climate change is increasingly recognized as a major public health challenge with wide-ranging effects on health conditions, including skin cancer. Rising global temperatures and heightened ultraviole…