Category: Research
Adjuvant cemiplimab therapy led to longer disease-free survival than placebo among patients at high risk for recurrence of cutaneous SCC
Background: Patients who have cutaneous squamous-cell carcinoma with high-risk features are at risk for recurrence after definitive local therapy. The benefit of systemic adjuvant therapy options has …
Aotearoa’s skin cancer crisis: key challenges and opportunities for strengthening sun safety policy, drawing on recent research and strategic recommendations
Each year, Aotearoa New Zealand’s (NZ) health system treats tens of thousands of skin cancers, the country’s most common cancer. This places a significant and avoidable burden on our healthcare system…
Outcomes of solid organ transplant recipients with advanced cancers receiving immune checkpoint inhibitors
Importance: Immune checkpoint inhibitors (ICIs) have improved overall survival in patients with advanced-stage cancers. However, data on their efficacy and safety in solid organ transplant recipients…
Commercial sunbeds should be banned in the UK
Indoor tanning is experiencing a boom in popularity, particularly among Gen Z (born 1997-2012), with social media promoting sunbeds as integral to wellness. Recent surveys report that 28% of the UK pu…
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ASPREE trial: Aspirin did not significantly affect keratinocyte carcinoma (KC) incidence in older Australians, but decreased the rate of multiple KC
Keratinocyte carcinomas (KC) are the most frequent cancers diagnosed in Australia and impart the largest economic cost of all cancers. Predisposed individuals tend to develop multiple KC over their li…
Clinical, pathological and molecular characteristics of patients with disease recurrence despite pathologic response to neoadjuvant ipilimumab plus nivolumab in stage III melanoma
Background: Pathologic response has been shown to be strongly associated with long-term event-free survival after neoadjuvant ipilimumab plus nivolumab in stage III melanoma. Only a small proportion o…
Impact of lidocaine concentration on analgesic efficacy and adverse events in dermatologic infiltrative anesthesia
Introduction: Infiltrative anesthesia with lidocaine plays a vital role in pain management during dermatologic procedures, ensuring patient comfort throughout the process. Objective: We aimed to in…
Uveal melanoma: a clear need exists to better define local practices and outcomes to inform future surveillance guidelines
Background: Uveal melanoma (UM) is the most common primary intraocular tumour. Despite effective local therapies, UM has a high risk of metastatic recurrence, most frequently to the liver. A signific…
Reduction in survival among melanoma survivors with second primary cutaneous and non-cutaneous melanoma
Background: Melanoma survivors have a high risk of developing second primary neoplasms, both cutaneous melanoma (SPCM) and non-cutaneous melanoma (SPNCM), but little is known about the survival impac…
Utility of rhenium-SCT as a single-session, non-invasive treatment for non-melanoma skin cancer: 1-year results from EPIC-skin study
Purpose: Rhenium-skin cancer therapy (SCT) is an innovative, noninvasive radionuclide treatment for nonmelanoma skin cancer (NMSC), which is administered in a single outpatient treatment session. A gl…